The epic story of the first contact, encounter, approach, betrayal and, eventually, life-transcending friendship, between Karamakate, an Amazonian shaman, last section of his people, and also two boffins who, within the course of 40 decades, travel through the Amazon in search of a sacred plant which could heal them. Inspired by the journals of their explorers of Theodor Koch-Grunberg the Amazon and also Richard Evans Schultes.